Estimation of Blood Urea Nitrogen as an Indicator of Severity in Acute Pancreatitis

ABSTRACT

Acute pancreatitis (AP) is an acute inflammatory process of the pancreas with variable involvement of the pancreas, regional tissues around the pancreas, or remote organ systems. The aim of study was to evaluate Blood urea nitrogen (BUN) as an indicator of severity and single prognostic indicator in acute pancreatitis and to Compare BUN with Ranson’s and BISAP criteria in prediction of SAP and mortality. Methods: A prospective observational study, total 72 patients participated in this study. All Patients presenting to the Emergency and Outpatient Departments of Medicine, Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar from October 2015 to September 2016 with suspicion of acute pancreatitis. Results: In the study, of these 66 (91.7%) were male and 6 (8.3%) were female. Mean age of the study subjects was 38.47 + 11.01. Mean age of patients with SAP was slightly higher than with non severe pancreatitis (41.89 vs. 37.33) but not statistically significant (p=0.55). 75% of the Pancreatitis was due to alcohol (54 out of 72), followed by gallstones in 13.88% (10/72). Conclusion: BISAP score within the first 24 hours of admission stratifies patients according to their risk of mortality and onset of organ failure.