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Botulinum toxin A in the early treatment of sixth nerve palsy in type 2 diabetes
Indian J Ophthalmol ; 2019 Jul; 67(7): 1133-1136
Artículo | IMSEAR | ID: sea-197356
ABSTRACT

Purpose:

Our study aims at evaluating the efficacy and safety of botulinum toxin A in the early treatment of sixth nerve palsy in type 2 diabetic patients.

Methods:

This study is a prospective and interventional clinical case series of patients presenting with acute onset of sixth cranial nerve palsy, who received injection botulinum toxin A.

Results:

Thirty-one cases were included in the study. 58% of the study subjects had incomplete palsy at presentation (abduction deficit -1 to -3) and 42% had complete palsy (-4 and -5). The median dosage of injection was 5 U (range 3--6 U). The median follow-up period is 2 months. The P value shows that there is statistically significant improvement in head turn, ocular deviation in primary position, and improvement in abduction between baseline and 1 week (P-value <0.001), 1 month (P-value <0.001) and 2 month (P-value <0.001) postinjection follow-up visits. 90.3% of patients had full resolution of symptoms in the last follow-up visit. 83.9% of patients were successfully treated.

Conclusion:

Early injection of botulinum toxin A in select patients with acquired sixth nerve palsy due to diabetes is a safe and efficient treatment option in alleviating symptoms, restoring function and quality of life and reducing need for surgical interventions in future.

Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Revista: Indian J Ophthalmol Año: 2019 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Revista: Indian J Ophthalmol Año: 2019 Tipo del documento: Artículo