Association Between Neonatal Thyroid Stimulating Hormone Status and Maternal Urinary Iodine Status
Indian Pediatr
;
2019 Jun; 56(6): 472-475
Artículo
| IMSEAR
| ID: sea-199225
ABSTRACT
Background:
Maternal urinary iodine concentration (MUIC) andpercentage of neonates with Thyroid stimulating hormone (TSH)>5 mIU/L are amongst the parameters suggested for assessingadequate iodine status.Objective:
To assess the correlation between MUIC andneonatal TSH levels.Studydesign:
Cross-sectional.Settings Tertiary care center in Delhi, India, between November2015 to November 2016.Participants:
Postnatal mother-neonate dyads.Methods:
TSH levels assessed among neonatal samples werestratified as below and above 5 mIU/L. MUIC was measured in544 mothers, 400 mother-neonate dyads with neonatal TSHlevels >5 mIU/L (cases) and 144 mother-neonate newbornmother dyads with neonatal TSH <5 mIU/L (controls).Results:
The percentage of mothers with iodine insufficiency(9.8% vs 5.6%) as well as iodine excess (54.3% vs 41.7%) weresignificant higher in cases than controls. Mean TSH was alsohigher (P=0.0002) in both the iodine deficient and iodine excessgroup. There was no correlation between neonatal TSH valuesand MUIC.Conclusions:
Lack of correlation between neonatal TSH andMUIC is due to iodine excess together with iodine deficiency.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Revista:
Indian Pediatr
Año:
2019
Tipo del documento:
Artículo
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