Clinicopathological Profile of Thrombocytopenia in Sitapur and Shahjahanpur Districts of Uttar Pradesh

ABSTRACT

Introduction: Thrombocytopenia is common haematologicalfinding with different specific etiologies. The aim ofpresent study was to find clinicopathological correlation ofthrombocytopenia in adults by causes, severity and clinicalpresentation.Material and Methods: This was a cross sectional studydone for a period of 6 months. After clinical profile laboratorydata and complications of patients with a platelet count of lessthan 1,50,000 were analyzed and tabulated.Results: The total sample size was 135 with 95(70.37%) malesand 40 (29.63%) females. Out of 135 patients, 32(23.70%)were diagnosed dengue. Malaria was found in 20% patients.Most cases were presented with fever(56%) followed bybodyache (40.74%), joint pain(33.33%), bleeding (17.03%)and hepatosplenomegaly(15.55%).Conclusion: Infectious diseases were the most common causeof thrombocytopenia out of which dengue was commonestfollowed by malaria and typhoid. Early recognition anddiagnosis of cause of thrombocytopenia can avoid bleedingmanifestations and serious complications.