Study of Frozen Section and Lymph Node in Management of Mucinous Ovarian Tumors

ABSTRACT

Introduction: Misdiagnosis of histologic type on frozensection could result in incomplete surgical staging of a moreaggressive ovarian cancer, ultimately leading to an inabilityto prognosticate, inappropriate treatment, need for repeatsurgery, and decreased survival. Study aimed to investigatethe discordance rate of the frozen section with final pathologyin the diagnosis of mucinous histology in ovarian tumors.Material and Methods: In this retrospective study cases ofmucinous ovarian tumor on frozen section or final pathologywere included from 2012 to 2018. Cases reporting a mucinousthe ovarian tumor on frozen section or final pathology wereidentified. Frozen section results were compared with finaldiagnosis to calculate concordance rates.Results: Of the 38 cases reported to be mucinous on frozensection, 36 had mucinous histology confirmed on finalpathology (94.7% concordance). Among the 36 mucinoustumors found to be concordant in mucinous histologic type onfrozen section and final pathology, there was a 61.1% (22/36)concordance rate on the classification of malignancy. Lymphnode dissection was performed in 12 of the 38 cases reportedto be mucinous on frozen section.Conclusion: All of these distinctions provide significantevidence that mucinous ovarian tumors should be approachedsurgically as a distinct entity