A Randomized Control Trial Comparing the Efficacy of Polydiaxanone II and Polypropylene Suture Material for Midline Vertical Abdominal Incision Using Interrupted X Sutures in Prevention of Burst Abdomen

ABSTRACT

Background: Abdominal wound dehiscence is a commoncomplication of emergency laparotomy. Its prevention inimportant to reduce postoperative morbidity and mortality. Theaim of this study to compare the incidence and risk of burstabdomen, wound infection and sinus formation withPolydiaxanone (PDS II) versus Polypropylene (PPL) in midlinelaparotomy wounds.Materials and Methods: 60 patients undergoing laparotomythrough a midline vertical incision were randomized afterinformed consent, to either a Polydiaxanone (PDS II) versusPolypropylene (PPL) suture material. The incidence andrelative risk (RR) of burst abdomen, wound infection and sinusformation using Polypropylene (PPL) group as the referencecategory were calculated.Results: There was 1 burst abdomen (out of 30 cases, 3.3%)in Polypropylene (PPL) group and none (out of 30) inPolydiaxanone (PDS II). The RR of burst could not becalculated because of 0 in one arm. The incidence of woundinfection was 16.6% in Polypropylene (PPL) (5 out of 30 cases)compared to 10% (3 out of 30 cases) in Polydiaxanone (PDSII). The relative risk (RR) of wound infection was 0.60. Theincidence of suture sinus was 10% (3 out of 30 cases) inPolypropylene (PPL) as compared to 3.3% in Polydiaxanone(PDSII) group.Conclusion: The risk of burst abdomen, wound infection &suture sinuses is less with the use of Polydiaxanone (PDS II).