In Vitro Antimicrobial Activity And Mic Of The Extracellular Ethyl Acetate Crude Extract Of Endophytic Fungi Fusarium Sp. Isolated From Tephrosia Purpurea Root
Int J Pharm Pharm Sci
;
2019 Mar; 11(3): 48-53
Artículo
| IMSEAR
| ID: sea-205854
ABSTRACT
Objective:
The objective of the present investigation was to find antimicrobial and MIC of endophytic fungi Fusarium sp. isolated from Tephrosia purpurea root.Methods:
Well diffusion assay was performed to find out the antimicrobial activity and Resazurin dye reduction method was performed to find out MIC of the extract.Result:
The extract showed the highest zone of inhibition of 22.66±0.57 mm, (Bacillus subtilis, MTCC-441) for Gram-positive bacteria and 20.66±0.57 mm, (E. coli, MTCC-443) for Gram-negative bacteria. Furthermore, the MIC of the extract was found to be (31.25 µg/ml-125 µg/ml).Conclusion:
Hence, the endophytic fungi isolated from the Tephrosia purpurea root, i.e. Fusarium sp. showed good antimicrobial activity and hence can be used to find a novel drug.
Texto completo:
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Índice:
IMSEAR (Asia Sudoriental)
Revista:
Int J Pharm Pharm Sci
Año:
2019
Tipo del documento:
Artículo
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