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Production of a new antibacterial antibiotic from a mutated strain of Streptomyces kanamyceticus M27 in submerged fermentation.
Hindustan Antibiot Bull ; 2005-2006; 47-48(): 1-6
Artículo en Inglés | IMSEAR | ID: sea-2082
ABSTRACT
A new antibacterial antibiotic was produced (136.5 microg/ml) using a 5 L EYELA Fermenter using 2 L fermentation medium at temperature 27 degrees C, pH 7.2, agitator speed 200 rpm, aeration rate 1 vvm having KLa 251.74 hr(-1) at 96 hrs. The optimised conditions for antibiotic using washed cells of the selected strain are pH 7.2, temperature 27 degrees C, age of the biomass 72 hr, amount of washed cell 4 g in 50 ml normal saline, incubation time 72 hr. The antibacterial activity of the fermented broth was also examined against some bacterial species and it was found that it is active against gram positive as well as gram negative bacteria.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Streptomyces / Bacterias / Microbiología Industrial / Biomasa / Fermentación / Antibacterianos Idioma: Inglés Revista: Hindustan Antibiot Bull Año: 2005 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Streptomyces / Bacterias / Microbiología Industrial / Biomasa / Fermentación / Antibacterianos Idioma: Inglés Revista: Hindustan Antibiot Bull Año: 2005 Tipo del documento: Artículo