A Study of the Effect of Cigarette Smoking on Lipid Profile of People of Kolhan Region

ABSTRACT

Introduction: Cigarette smoking is an important and independent risk factor of atherosclerosis, coronary artery disease, andperipheral vascular disorders. It adversely affects the concentration of the plasma lipids and lipoprotein levels.Materials and Methods: The present study was conducted in the Department of Physiology, Mahatma Gandhi MemorialMedical College and Hospital, Jamshedpur. Sixty healthy cigarette smokers were compared with forty healthy age-matched,non-obese, non-smokers. Participants in both the groups were in the age range of 25–35 years having no history of alcoholabuse or diseases such as diabetes mellitus and hypertension.Conclusion: Total cholesterol and low-density lipoprotein (LDL) showed a highly significant upper range in smokers withP < 0.001. High-density lipoprotein and very LDL were also increased to a partially significant level in smokers with P < 0.1.