Effect of Pitavastatin in Patients with Active Rheumatoid Arthritis Treated at a Tertiary Care Hospital
Artículo
| IMSEAR
| ID: sea-209238
ABSTRACT
Introduction:
Rheumatoid arthritis (RA) is a chronic systemic inflammatory disorder, autoimmune in nature that predominatelyaffects synovial joints. Being a crippling disease is a leading cause of disability that often reduces the quality of life and impairspatients ability to work.Aims andObjectives:
The aim of the study was to compare the effect of different treatment regimens on patients with activeRA treated at a tertiary care hospital.Materials andMethods:
This was a prospective, open labeled, parallel arm, randomized, and single-center study performed ina tertiary care teaching hospital (Chennai Medical College Hospital and Research Centre [SRM Groups], Irungalur, Tiruchirapalli)and was conducted at outpatient clinics. Total duration of the study period was 24 weeks. All the patients were having activeRA and were on oral methotrexate (first-line disease-modifying antirheumatic drug) at the time of recruitment.StatisticalAnalysis:
All the data were initially entered into Microsoft Excel 2010 and later these spreadsheets were used foranalysis. Statistical analysis was done using SPSS version 20.0.Conclusion:
Combination therapy of pitavastatin and methotrexate is better than methotrexate monotherapy and combinationtherapy of rosuvastatin and methotrexate.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Tipo de estudio:
Ensayo Clínico Controlado
Año:
2019
Tipo del documento:
Artículo
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