Computed tomography-guided percutaneous cryoablation for lung ground-glass opacity: A pilot study

ABSTRACT

Context Ground-glass opacity (GGO) is a nonspecific imaging parameter for early-stage pulmonary cancer. In these cases, a definite diagnosis and prompt surgery usually yield satisfactory outcomes. Aims: This study aimed to assess the safety and feasibility of cryoablation treatment for lung GGO. Subjects and Methods: We reviewed the clinical data of 14 patients (19 lung tumors) with lung GGO and evaluated the adverse events, lung function, and treatment efficacy after cryoablation. Statistical Analysis Used Statistical analyses were performed using the Statistical Package for the Social Sciences software (version 13.0; SPSS Inc., Chicago, IL, USA). Results: None of the patients exhibited serious complications, and lung function recovered to >95% after 1 month. During a follow-up, computed tomography scan at 24 months, the GGO appeared to have been successfully ablated in all patients. Conclusion: Cryoablation may serve as a safe and feasible option for the treatment of GGO.