Acute hepatitis induced by a single dose of hydroxychloroquine

ABSTRACT

Hydroxychloroquine(HCQ)is considered the drug of choice for prophylaxis of COVID-19. It is supposed to be a safe drug. Herein we describe a case where a single dose of HCQ has led to acute toxic hepatitis. A junior of CIMS, Bilaspur while working at surgery department took a single dose of HCQ and suffered from jaundice. This suggests that we cannot label any drug to be safe and should take drug only after proper medical consultation and prescription without which even a single dose can cause hypersensitivity reaction