Development & use of antichlamydial monoclonal antibodies for rapid diagnosis of follicular conjunctivitis.
Artículo
en Inglés
| IMSEAR
| ID: sea-21562
ABSTRACT
We developed four independent murine hybrid clones producing IgG class and genus specific monoclonal antibodies against the major outer membrane protein (MOMP) of Chlamydia trachomatis, L2 serovar. All antibodies reacted with a single epitope of MOMP. In indirect immunofluorescence assay using one of the antibodies chlamydiae could be detected in 12 of 23 conjunctival scrapings from patients of follicular conjunctivitis. Giemsa staining could detect classical inclusion bodies in only 5 of these 23 smears. Antigen detection using these monoclonal antibodies may be used as a rapid diagnostic test in clinical and epidemiological screening for chlamydial infection.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Factores de Tiempo
/
Chlamydia trachomatis
/
Conjuntivitis Bacteriana
/
Animales
/
Ratones
/
Anticuerpos Monoclonales
Idioma:
Inglés
Año:
1994
Tipo del documento:
Artículo
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