Comparative Analysis of Amoebic Liver Abscess versus Pyogenic Liver Abscess on Clinical and Investigative Consequences

ABSTRACT

An attempt was made to compare the analysis of investigative parameters to distinguish Amoebic Liver Abscess (ALA) from Pyogenic Liver Abscess (PLA). This study was carried out at Calcutta National Medical College & Hospital, Kolkata 700014. Patients were included with signs and symptoms suggestive of Liver Abscesses. The investigations of Serological, Hematological, Biochemical, Radiological and CT scan were done. Antimicrobial Therapy, Image Guided Percutaneous Aspirations/Drainage or Open surgical Drainage was performed and checked in follow-up visits up to 3 months. The highest incidences of Liver Abscess (53.3%) were encountered in alcoholic male. Fever and Abdominal Pain were common in both ALA and PLA. Hepatomegaly was significantly high (p<0.05) in PLA (64.2%) than ALA (37.5%), but jaundice was only noted in PLA (22.2%). E coli, K pneumonia and S aureus were confirmed in PLA. Alkaline Phosphatase was significantly high (p<0.05) in PLA. Right sided pleural effusion was noted in Chest X-ray of 50% case . USG studies measured 70% Solitary Abscesses with 5-10 cm in the Right Lobe. Partial resolution occurred in 28.6% of PLA and 31.2% of ALA. USG and Serological Tests are recommended and Conservative Management should be followed for ALA and invasive treatment for PLA patients