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Molecular characterization of the severe falciparum malaria with typhoid co-infection A case report
J Vector Borne Dis ; 2022 Jan; 59(1): 105-107
Artículo | IMSEAR | ID: sea-216859
ABSTRACT
Malaria and typhoid co-infections can be a serious public health issue in tropical countries leading to incorrect diagnosis due to overlapping clinical presentations of malaria and typhoid and hence, causing a delay in implementing the appropriate treatment regimen for these concurrent infections. This study reports a case of six-year-old female child co-infected with severe malaria (Plasmodium falciparum) and typhoid (Salmonella typhi) diagnosed by rapid malaria antigen test (RMAT) and blood culture respectively. Further, analysis of the chloroquine resistance gene Pfcrt for the falciparum demonstrated the presence of K76T mutant allele in pfcrt gene with high IC50 (150nM) for chloroquine (CQ) drug. The present case highlights the significance of timely identification and treatment of co-infections and also provides information about the circulating P. falciparum clinical strains.

Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Revista: J Vector Borne Dis Asunto de la revista: Parasitology / Tropical Medicine Año: 2022 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Revista: J Vector Borne Dis Asunto de la revista: Parasitology / Tropical Medicine Año: 2022 Tipo del documento: Artículo