Evaluation of cyclosporine-A obtained from Tolypocladium sp. for immunosuppressive potential.
Artículo
en Inglés
| IMSEAR
| ID: sea-21689
ABSTRACT
Cyclosporine-A obtained from an indigenous isolate of Tolypocladium sp. was evaluated for immunosuppressive potential by skin grafting in rats using the commercially available Sandimmune as reference at 15 and 30 mg/kg/day for a period of 14 days. The Sandimmune treated animal group showed 83 per cent acceptance of skin grafts while the test preparation treated group showed 67-83 per cent acceptance. The degree of nephro- and hepatotoxicity was comparable for both the preparations.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ratas
/
Femenino
/
Masculino
/
Trasplante de Piel
/
Ciclosporina
/
Hongos Mitospóricos
/
Rechazo de Injerto
/
Animales
Idioma:
Inglés
Año:
1991
Tipo del documento:
Artículo
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