Assessment of Malaria by 5 Part Cell Counters CBC Analysis to Improve the Sensitivity and Specificity of Diagnosis

ABSTRACT

This study is undertaken to compare efficacy of peripheral smear (PS) and malarial antigen methods (contemporary methods of malaria diagnosis) and 5 part haematology cell counter scatterogram and flagging's in cases of malaria for effective treatment and reducing morbidity and mortality. The study was conducted by selecting 60 cases on strong clinical suspicion, first PS and antigen test was done followed by 5 part haematological cell counter for CBC. Results were subjected to statistical analysis. CBC has a sensitivity and specificity of 96.66% and 50%respectively while peripheral smear showed 96.15% sensitivity and 16.66% specificity for detection of malaria. Antigen has sensitivity of 98.24% and specificity of 93.6%. The study proved that various diagnostic modalities to diagnose malaria are far much better than only one diagnostic method.