Evaluation of Efficacy of DAB for Phi Bodies in Acute Leukemia

ABSTRACT

Diagnosing the type and sub-type of Leukemia is very important as the therapy, prognosis and survival rate changes with each type and sub-type. In the present study French American British (FAB) morphological classification is used and 60 % cases of Leukemia were evaluated by studying the detailed clinical features, morphology on peripheral blood smear and bone marrow aspiration. Out of the 60 cases we found that 40 cases were of acute Leukemia and 20 cases of chronic Leukemia. Out of which 24 were of acute Myeloid Leukemia, 16 of acute Lymphoid Leukemia. There were 15 cases of CML and 5 cases of CLL. Phi bodies appear to be characteristics of immature Myeloid cells in Leukemia and are seen with a higher frequency than Auer rods in acute Myeloid Leukemia