A modified model of glaucoma filtering surgery in Sprague-Dawley rats
Indian J Ophthalmol
;
2022 Feb; 70(2): 662-664
Artículo
| IMSEAR
| ID: sea-224162
ABSTRACT
Animal models are useful in glaucoma research to study tissue response to wound healing. Smaller animals such as rats offer additional advantages in terms of availability of detection antibodies and microarrays with cheaper maintenance costs. In this study, we describe a glaucoma filtering surgery (GFS) model in adult Sprague–Dawley rats by performing a sclerostomy using a 26?G needle and additionally placing a silicone tube (27 G) connecting the anterior chamber to the subconjunctival space to maintain a patent fistula for the flow of aqueous humor, thus providing a more definitive bleb. This technique will be useful in identifying and modifying newer targets in the wound healing process in order to improve surgical outcomes following GFS
Texto completo:
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Índice:
IMSEAR (Asia Sudoriental)
Revista:
Indian J Ophthalmol
Año:
2022
Tipo del documento:
Artículo
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