Hepatoprotective activity of silymarin against hepatic damage in Mastomys natalensis infected with Plasmodium berghei.
Artículo
en Inglés
| IMSEAR
| ID: sea-23926
ABSTRACT
Silymarin, a flavolignan from the seeds of Silybum marianum, showed significant hepatoprotective activity in P. berghei-induced hepatic damage in M. natalensis, as assessed by changes in several serum and liver biochemical parameters. Changes in lipoprotein-X, GOT, GPT, alkaline phosphatase and bilirubin were found to be protected by silymarin at different doses. Maximum activity was observed at a dose of 5 mg/kg bw, po. Silymarin had no effect on parasitaemia.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Plasmodium berghei
/
Silimarina
/
Flavonoides
/
Masculino
/
Modelos Animales de Enfermedad
/
Relación Dosis-Respuesta a Droga
/
Hepatitis Animal
/
Pruebas de Función Hepática
/
Animales
/
Malaria
Idioma:
Inglés
Año:
1989
Tipo del documento:
Artículo
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