Effect of trisodium pentetat on the distribution of cadmium in some body organs & on hepatic metallothionein in rats.
Artículo
en Inglés
| IMSEAR
| ID: sea-24369
ABSTRACT
The pre- and post-treatment with calcium trisodium diethylene-triaminepentaacetic acid (CaNa3DTPA) was investigated for their efficacy to mobilize cadmium (Cd) from various tissues and hepatic metallothionein (MT) in Cd-exposed rats. Pretreatment with CaNa3 DTPA significantly reduced the hepatic and renal Cd absorption while, post Cd treatment with CaNa3 DTPA was effective in reducing renal and brain Cd. Pretreatment with CaNa3DTPA significantly increased the Cd induced hepatic metallothionein (MT) level, MT-bound Cd, Zn and Cu contents while, post treatment with CaNa3DTPA reduced the hepatic MT, MT-bound Cd compared to Cd alone treated rats.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ratas
/
Femenino
/
Cadmio
/
Intoxicación por Cadmio
/
Distribución Tisular
/
Ácido Pentético
/
Hígado
/
Animales
/
Metalotioneína
Idioma:
Inglés
Año:
1989
Tipo del documento:
Artículo
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