Quantitative structure activity relationship in diphenyl ureas for insect growth regulating activity.
Artículo
en Inglés
| IMSEAR
| ID: sea-25095
ABSTRACT
Insect growth regulating (IGR) activity of 29 diphenyl urea compounds was determined against the filariasis vector, Culex quinquefasciatus. The variations in the activity of these compounds were analysed with the physicochemical substituent parameters and regression analysis. Quantitative structure activity relationship (QSAR) studies revealed that the IGR activity was influenced by lipophilicity, electron withdrawing effect of the substituents on the aniline moiety, the steric effect of the substituents in the acidic moiety and the position of substitution. This diphenyl ureas for IGR activity seem to offer a successful model for the application of QSAR method in the development of new vector control agents.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Relación Estructura-Actividad
/
Carbanilidas
/
Análisis de Regresión
/
Culex
/
Insectos Vectores
/
Animales
Tipo de estudio:
Estudio diagnóstico
Idioma:
Inglés
Año:
1991
Tipo del documento:
Artículo
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