Role of virulence plasmid of Aeromonas hydrophila in the pathogenesis of ulcerative disease syndrome in Clarias batrachus.
Indian J Biochem Biophys
;
2007 Oct; 44(5): 401-6
Artículo
en Inglés
| IMSEAR
| ID: sea-26804
ABSTRACT
Pathogenic Aeromonas hydrophila (strain VB21), a multiple-drug resistance strain contains a plasmid of about 21 kb. After curing of plasmid, the isolates became sensitive to antimicrobials, to which they were earlier resistant. The cured bacteria exhibited significant alterations in their surface structure, growth profile and virulence properties, and failed to cause ulcerative disease syndrome (UDS) when injected into the Indian catfish Clarias batrachus. Routine biochemical studies revealed that the plasmid curing did not alter the biochemical properties of the bacteria. After transformation of the plasmid into cured A. hydrophila the bacterium regained its virulence properties and induced all the characteristic symptoms of UDS when injected into fish. Thus, the plasmid plays a pivotal role in the phenotype, growth and virulence of A. hydrophila and pathogenesis of aeromonad UDS.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Plásmidos
/
Úlcera
/
Bagres
/
ADN Bacteriano
/
Infecciones por Bacterias Gramnegativas
/
Aeromonas hydrophila
/
Enfermedades de los Peces
/
Animales
Tipo de estudio:
Estudio de etiología
Idioma:
Inglés
Revista:
Indian J Biochem Biophys
Año:
2007
Tipo del documento:
Artículo
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