Effect of anticalmodulin and antitubulin on LDL-receptor synthesis in aortic smooth muscle cells cultured in vitro.
Indian J Biochem Biophys
;
1990 Aug; 27(4): 251-3
Artículo
en Inglés
| IMSEAR
| ID: sea-27445
ABSTRACT
Effect of trifluoperazine and colchicine on LDL-receptor synthesis in smooth muscle cells exposed to hypercholesterolemic medium in vitro have been studied. While trifluoperazine at 25 microM concentration caused stimulation of LDL-receptor synthesis, colchicine acted as a dose-dependent inhibitor of LDL-receptor synthesis. Thus calmodulin down regulates LDL-receptor synthesis independent of microtubular involvement.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Trifluoperazina
/
Calmodulina
/
Receptores de LDL
/
Células Cultivadas
/
Colchicina
/
Moduladores de Tubulina
/
Animales
/
Músculo Liso Vascular
Idioma:
Inglés
Revista:
Indian J Biochem Biophys
Año:
1990
Tipo del documento:
Artículo
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