Cellular AATF gene: armour against HIV-1.
Indian J Biochem Biophys
;
2007 Oct; 44(5): 276-8
Artículo
en Inglés
| IMSEAR
| ID: sea-27966
ABSTRACT
Outcome of HIV-1 infection at the cellular level is decided by the orchestrated balance that exists between cellular nucleic acid-based adaptive immune mechanism involving non-coding micro RNAs (miRNAs) and offensive tactics of HIV-1 to suppress this host cellular immunity. In this context, the review explains the importance of a novel miRNA encoded exclusively and conspicuously by HIV-1 genome that has the ability to specifically target cellular AATF gene recognized to play a crucial role in the maintenance of adaptive immunity at nucleic acid level against HIV-1 invasion.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Proteínas Represoras
/
Factores de Transcripción
/
Humanos
/
Fenómenos Fisiológicos Celulares
/
VIH-1
/
Apoptosis
/
MicroARNs
/
Proteínas Reguladoras de la Apoptosis
Idioma:
Inglés
Revista:
Indian J Biochem Biophys
Año:
2007
Tipo del documento:
Artículo
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