HLA and filariasis in Sri Lankans and Indians.

Chan, S H; Dissanayake, S; Mak, J W; Ismail, M M; Wee, G B; Srinivasan, N; Soo, B H; Zaman, V

Chan, S H; Dissanayake, S; Mak, J W; Ismail, M M; Wee, G B; Srinivasan, N; Soo, B H; Zaman, V.

Southeast Asian J Trop Med Public Health ; 1984 Sep; 15(3): 281-6

Artículo en Inglés | IMSEAR | ID: sea-31883

ABSTRACT

ABSTRACT

Similar HLA association was found in patients with elephantiasis in Sri Lankans and Southern Indians. HLA-B15 was observed in 13/44 (30%) Sri Lankan patients with elephantiasis compared to 1/27 (4%) Sri Lankan controls (p = .0058; RR = 10.9) and in 5/8 (28%) Southern Indian elephantiasis compared to 10/101 (10%) Southern Indian controls (p = 0.04; RR = 3.5). In combining the data, the significance of the difference of the frequency of B15 between patients with elephantiasis and controls was even more marked (p = 0.00045; corrected p = 0.012; RR = 4.4).

Asunto(s)

Pueblo Asiatico; Susceptibilidad a Enfermedades; Elefantiasis/genética; Femenino; Filariasis/genética; Antígenos HLA/genética; Humanos; Linfedema/genética; Malasia; Masculino; Singapur; Sri Lanka

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Singapur / Sri Lanka / Femenino / Humanos / Masculino / Pueblo Asiatico / Susceptibilidad a Enfermedades / Elefantiasis / Filariasis / Antígenos HLA País/Región como asunto: Asia Idioma: Inglés Revista: Southeast Asian J Trop Med Public Health Año: 1984 Tipo del documento: Artículo

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