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The aromatic ethylamide derivative of retinoic acid in the treatment of acne vulgaris.
Southeast Asian J Trop Med Public Health ; 1977 Sep; 8(3): 311-6
Artículo en Inglés | IMSEAR | ID: sea-32569
ABSTRACT
A clinical trial on the aromatic ethylamide derivative of retinoic acid (Ro. 11-1430) applied topically was carried out for 10 weeks on 50 ambulatory patients suffering from various degrees of acne vulgaris. This clinical trial assessed the efficacy and side reactions of Ro. 11-1430 in the treatment of acne vulgaris, especially when used in the tropics. A comparison was made between the results obtained in this trial and those in another trial using topical retinoic acid. Analysis made in terms of efficacy, drug tolerance, patients' complaints and duration of treatment for achieving obvious alleviation of symptoms shows that Ro. 11-1430, with the exception of side reactions due to the drugs applied, was inferior to retinoic acid. Relapses as well as remissions often occurred during the period of maintenance therapy. Like retinoic acid, Ro. 11-1430 has a palliative effect only and not a curative one.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Factores de Tiempo / Tretinoina / Vitamina A / Femenino / Humanos / Masculino / Niño / Adolescente / Acné Vulgar Tipo de estudio: Ensayo Clínico Controlado Idioma: Inglés Revista: Southeast Asian J Trop Med Public Health Año: 1977 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Factores de Tiempo / Tretinoina / Vitamina A / Femenino / Humanos / Masculino / Niño / Adolescente / Acné Vulgar Tipo de estudio: Ensayo Clínico Controlado Idioma: Inglés Revista: Southeast Asian J Trop Med Public Health Año: 1977 Tipo del documento: Artículo