Hydrophobicity and antifilarial activities of 4-aminoquinolines.
Southeast Asian J Trop Med Public Health
;
1982 Dec; 13(4): 658-61
Artículo
en Inglés
| IMSEAR
| ID: sea-32613
ABSTRACT
The apparent partition coefficients (Papp.) of eight 4-aminoquinolines in 1-octanol/pH 7.4 buffered solutions have been determined and correlated with their reported antifilarial activities. Antifilarial activity appears to be present only in those 4-aminoquinolines which have log Papp. values falling within a narrow range of 2.8 to 3.2.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Solubilidad
/
Química
/
Química Física
/
Fenómenos Químicos
/
Filaricidas
/
Aminoquinolinas
/
Antihelmínticos
Idioma:
Inglés
Revista:
Southeast Asian J Trop Med Public Health
Año:
1982
Tipo del documento:
Artículo
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