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Lymphocyte transformation in lepromatous leprosy: a study of the influence of disease activity and symptom duration.
Southeast Asian J Trop Med Public Health ; 1986 Mar; 17(1): 104-10
Artículo en Inglés | IMSEAR | ID: sea-33403
ABSTRACT
The lymphocyte hyporesponsiveness to M. leprae of patients with active lepromatous leprosy has been well described. This immune defect is less well understood in terms of its time of origin, possible reversibility and specificity. To further examine the persistence and specificity of this abnormality, lymphocyte transformation tests of 93 leprosy patients to lepromin, BCG and PHA were studied. Among lepromatous patients, a decreased response to M. leprae was seen, whether the disease was active or inactive. Decreased responses to BCG were found in lepromatous patients with active disease, but not in those with inactive disease. The duration of patient symptoms was not associated with differences in LTT responses among the active lepromatous patients.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Fitohemaglutininas / Humanos / Masculino / Vacuna BCG / Activación de Linfocitos / Adolescente / Adulto / Lepromina / Lepra / Persona de Mediana Edad Idioma: Inglés Revista: Southeast Asian J Trop Med Public Health Año: 1986 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Fitohemaglutininas / Humanos / Masculino / Vacuna BCG / Activación de Linfocitos / Adolescente / Adulto / Lepromina / Lepra / Persona de Mediana Edad Idioma: Inglés Revista: Southeast Asian J Trop Med Public Health Año: 1986 Tipo del documento: Artículo