Immunodiagnosis of clonorchiasis by enzyme-linked immunosorbent assay.
Southeast Asian J Trop Med Public Health
;
1988 Mar; 19(1): 117-21
Artículo
en Inglés
| IMSEAR
| ID: sea-33475
ABSTRACT
The present study applied the indirect enzyme-linked immunosorbent assay (ELISA) technique in the immunodiagnosis of clonorchiasis. Antigen used in this study was extracted from adult worms of Clonorchis sinensis obtained from cats. 132 patients with clonorchiasis, 100 healthy persons and 14 patients with other parasitic infections were studied. Mean O.D. ratio with standard deviation of clonorchiasis was 1.41 +/- 0.21 with 0.95 +/- 0.13 of healthy persons. Results revealed 90.2% to 95.5% of sensitivity and 84% to 99% specificity dependent on the two cut off values of O.D. ratio, i.e. 1.10 and 1.20. Antibody titers derived from O.D. ratio highly correlated with direct titration (Y = 0.0303 +/- 1.1766 X, r = 0.8945). Cross reactions of other parasite infections to clonorchiasis were observed in patients with angiostrongyliasis and schistosomiasis.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Enfermedades Parasitarias
/
Humanos
/
Ensayo de Inmunoadsorción Enzimática
/
Pruebas Serológicas
/
Anticuerpos Antihelmínticos
/
Valor Predictivo de las Pruebas
/
Clonorquiasis
/
Clonorchis sinensis
/
Animales
Tipo de estudio:
Estudio diagnóstico
/
Estudio pronóstico
Idioma:
Inglés
Revista:
Southeast Asian J Trop Med Public Health
Año:
1988
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS