Maternal and newborn thyroid hormonal profile in a non-goitrous area of Myanmar.

ABSTRACT

Serum thyroxine (T4), triiodothyronine (T3) and thyrotropin (TSH) levels of 325 pairs of blood samples from the newborn infants and their mothers were determined with the aim of establishing the thyroid hormonal profile of the newborn babies and their mothers in a non-goitrous area of Myanmar. The mean +/- SEM cord serum T4, T3 and TSH levels were 117.47 +/- 1.92 nmol/l, 0.57 +/- 0.02 nmol/l and 6.41 +/- 0.84 mu/ml respectively. The corresponding maternal levels were 146.29 +/- 2.06 nmol/l, 2.33 +/- 0.04 nmol/l and 2.59 +/- 0.17 mu/ml maternal serum T4 and T3 levels were significantly higher than the corresponding cord serum values (p < 0.0001 in both cases) and maternal TSH level was significantly lower than cord level (p < 0.0001). Maternal and cord T4, T3 and TSH levels of premature infants were not significantly different from those of mature infants. Similarly maternal and cord hormonal levels of male infants were not significantly different from those of female infants.