Size distribution curves of blood cells in thalassemias and hemoglobin H diseases.
Southeast Asian J Trop Med Public Health
;
1992 ; 23 Suppl 2(): 79-85
Artículo
en Inglés
| IMSEAR
| ID: sea-34386
ABSTRACT
Thalassemias and hemoglobinopathies in Thailand have been examined with a blood cell counter based on electroimpedance principle and obtained size distribution curves of red cells and platelets. Among various disorders, beta-thalassemia/hemoglobin E and homozygous hemoglobin Constant Spring showed severe anemia. Their red cell size distribution curve shifted to the left and overlapped with the platelet size distribution curve. Red cell distribution width expressed by coefficient of variation and the degree of the overlapping were stronger in beta-thalassemia/HbE than HbH. Heterozygous beta-thalassemia showed a narrow red cell distribution curve width with small standard deviation and low England's value. Although the overlapping of size distribution curves cause inaccurate red cell count and platelet count, careful observation of the size distribution curves was proved to have high diagnostic value.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Recuento de Plaquetas
/
Tailandia
/
Índice de Severidad de la Enfermedad
/
Plaquetas
/
Humanos
/
Hemoglobina E
/
Hemoglobinas Anormales
/
Tamizaje Masivo
/
Sensibilidad y Especificidad
/
Impedancia Eléctrica
Tipo de estudio:
Estudio diagnóstico
/
Estudios de evaluación
/
Estudio pronóstico
/
Estudio de tamizaje
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Southeast Asian J Trop Med Public Health
Año:
1992
Tipo del documento:
Artículo
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