Automatic measurement of hemoglobin F in blood obtained from patients with hemoglobin E/E and beta-thalassemia/hemoglobin/E.
Southeast Asian J Trop Med Public Health
;
1992 ; 23 Suppl 2(): 91-4
Artículo
en Inglés
| IMSEAR
| ID: sea-34706
ABSTRACT
This paper presents an automated determination of hemoglobin (Hb) F in Hb E/E disease using Hi-Auto A1c. Blood specimens collected in Bangkok were frozen, and sent to Japan by air mail for the determination. The automatically determined values showed a high correlation with the values obtained by the classical alkali denaturation method. Hb E/E cases showed 4.24 +/- 1.75% of Hb F. On the other hand, Hb, Hct, MCV and MCH in the disease samples were lower than in the controls, but higher than those of beta-thalassemia/HbE disease. From the results it was concluded that Hb E/E could be differentiated from beta-thalassemia/HbE by combination of Hb F value and MCH or Hb in CBC.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Tailandia
/
Humanos
/
Hemoglobina Fetal
/
Hemoglobina E
/
Hemoglobinas
/
Recién Nacido
/
Reproducibilidad de los Resultados
/
Cromatografía Líquida de Alta Presión
/
Talasemia beta
/
Adulto
Tipo de estudio:
Estudio diagnóstico
/
Estudios de evaluación
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Southeast Asian J Trop Med Public Health
Año:
1992
Tipo del documento:
Artículo
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