Detection of carriers and prenatal diagnosis of bleeding disorders.
Southeast Asian J Trop Med Public Health
;
1993 ; 24 Suppl 1(): 37-40
Artículo
en Inglés
| IMSEAR
| ID: sea-34910
ABSTRACT
Carrier detection and prenatal diagnosis in the three commonest bleeding disorders (hemophilia A and B and von Wilebrands disease) can be performed either phenotypically or genotypically. Phenotypic analysis for carrier detection results only in a probabilistic assessment whereas DNA analysis, either by direct defect detection or by DNA polymorphism based gene tracking, can result in an accuracy of effectively 100%. Direct defect detection is the method of choice but can be technically demanding. Polymorphism analysis is much simpler and is now being used in family studies world wide.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Diagnóstico Prenatal
/
Enfermedades de von Willebrand
/
Humanos
/
Hemofilia B
/
Hemofilia A
/
Tamización de Portadores Genéticos
Tipo de estudio:
Estudio diagnóstico
Idioma:
Inglés
Revista:
Southeast Asian J Trop Med Public Health
Año:
1993
Tipo del documento:
Artículo
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