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Increased efficacy of liposomes-encapsulated praziquantel in treatment of opisthorchiasis in hamsters.
Southeast Asian J Trop Med Public Health ; 1983 Dec; 14(4): 501-4
Artículo en Inglés | IMSEAR | ID: sea-36223
ABSTRACT
An increased efficacy of liposomes-encapsulated praziquantel was observed in the treatment of hamster opisthorchiasis. A single intracardial dose of 1.5 mg/kg of encapsulated praziquantel is as effective as an intracardial dose of 30 mg/kg or an oral dose of 100 mg/kg of free praziquantel. The suppressing activity of both free and liposomes-encapsulated praziquantel significantly decrease as the infection times increase from 1 to 5 weeks, suggesting that the young liver flukes are more susceptible to praziquantel than the adult flukes.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Opistorquiasis / Praziquantel / Cricetinae / Mesocricetus / Isoquinolinas / Liposomas / Animales Idioma: Inglés Revista: Southeast Asian J Trop Med Public Health Año: 1983 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Opistorquiasis / Praziquantel / Cricetinae / Mesocricetus / Isoquinolinas / Liposomas / Animales Idioma: Inglés Revista: Southeast Asian J Trop Med Public Health Año: 1983 Tipo del documento: Artículo