Therapy of chronic idiopathic thrombocytopenic purpura in adults: experiences from Thailand.
Southeast Asian J Trop Med Public Health
;
1993 ; 24 Suppl 1(): 71-5
Artículo
en Inglés
| IMSEAR
| ID: sea-36229
ABSTRACT
Results of different types of treatment in 416 adults with chronic idiopathic thrombocytopenic purpura (ITP) were analyzed. Of 368 patients treated with corticosteroids, 278 (77%) achieved complete response (CR ie, normalization of platelet count). However, only 18% of patients had continued complete response (CCR). Results of splenectomy was analyzed in 126 patients, 49% of them achieved CCR and 76% of them had beneficial effects from the operation. Emergency splenectomy was a life saving procedure in 8 of 11 patients with life-threatening hemorrhage. Vinca alkaloids gave a 50% transient CR. Immunosuppressive agents (cyclophosphamide, azathioprine) resulted in only 11% CCR.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Esplenectomía
/
Tailandia
/
Alcaloides de la Vinca
/
Femenino
/
Humanos
/
Masculino
/
Prednisolona
/
Enfermedad Crónica
/
Resultado del Tratamiento
/
Púrpura Trombocitopénica Idiopática
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Southeast Asian J Trop Med Public Health
Año:
1993
Tipo del documento:
Artículo
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