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Acetylcholine receptor antibody in patients with myasthenia gravis.
Asian Pac J Allergy Immunol ; 1986 Dec; 4(2): 101-5
Artículo en Inglés | IMSEAR | ID: sea-36879
ABSTRACT
The determination of acetylcholine receptor antibody (AChR Ab) titer by an enzyme-linked immunosorbent assay (ELISA) in patients with myasthenia gravis was introduced. The optimal conditions were determined by chequerboard determination. The specificity was confirmed by inhibition tests. The sensitivity is 9 p mole. The comparison of AChR Ab titers among 49 myasthenic patients, 19 non-myasthenic neurological patients and 20 healthy blood donors has shown that it is a highly sensitive, specific, reproducible, rapid, simple and inexpensive method for determining AChR Ab and that it is highly valuable for the diagnosis of myasthenia gravis.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Autoanticuerpos / Humanos / Ensayo de Inmunoadsorción Enzimática / Cinética / Receptores Colinérgicos / Miastenia Gravis / Complejo Antígeno-Anticuerpo Idioma: Inglés Revista: Asian Pac J Allergy Immunol Año: 1986 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Autoanticuerpos / Humanos / Ensayo de Inmunoadsorción Enzimática / Cinética / Receptores Colinérgicos / Miastenia Gravis / Complejo Antígeno-Anticuerpo Idioma: Inglés Revista: Asian Pac J Allergy Immunol Año: 1986 Tipo del documento: Artículo