Allergic reactions to phenytoin in a general hospital in Singapore.
Asian Pac J Allergy Immunol
;
1996 Dec; 14(2): 65-8
Artículo
en Inglés
| IMSEAR
| ID: sea-37221
ABSTRACT
Phenytoin is used for the treatment and prevention of fits. We investigated all patients reported to have phenytoin allergy in our hospital and found 42 confirmed cases. Sixty-nine percent were female and 83.3% were Chinese. The mean age of the patients was 46.5 years. The reactions reported were maculopapular rash (71.4%), Stevens-Johnson syndrome (14.3%), fever (4.8%), generalized exfoliative dermatitis (2.4%), toxic epidermal necrolysis (2.4%), vasculitis (2.4%) and agranulocytosis (2.4%). In conclusion, the majority of reported allergic reactions to phenytoin were cutaneous (92.9%) and one fifth of these were potentially life-threatening.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Fenitoína
/
Singapur
/
Femenino
/
Humanos
/
Masculino
/
Estudios Retrospectivos
/
Adulto
/
Hipersensibilidad a las Drogas
/
Hospitales Generales
/
Anticonvulsivantes
Tipo de estudio:
Estudio observacional
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Asian Pac J Allergy Immunol
Año:
1996
Tipo del documento:
Artículo
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