Anticarcinogenic effects of an aqueous infusion of cloves on skin carcinogenesis.
Artículo
en Inglés
| IMSEAR
| ID: sea-38067
ABSTRACT
Spices and flavouring agents are now receiving increasing attention as many of them have been shown to have anticarcinogenic properties. Cloves, sun-dried unopened flower buds from the plant Syzygium aromaticum L, are commonly used as a spice and food flavour. The present study was designed to investigate the chemopreventive action of aqueous infusion of cloves on 9,10-dimethyl benz(a)anthracene (DMBA) and croton oil induced skin carcinogenesis in Swiss mice. The results indicate protection against skin papilloma formation in a dose dependent manner. It has been shown that oral administration of aqueous infusions of clove at a dose of 100 microl/mouse/day not only delays the formation of papilloma but also reduces the incidence of papilloma as well as the cumulative number of papillomas per papilloma bearing mouse. Our observations suggest a promising role for cloves in restriction of the carcinogenesis process.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Papiloma
/
Neoplasias Cutáneas
/
Extractos Vegetales
/
Carcinógenos
/
Transformación Celular Neoplásica
/
Administración Oral
/
Quimioprevención
/
9,10-Dimetil-1,2-benzantraceno
/
Eugenia
/
Animales
Idioma:
Inglés
Año:
2005
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS