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The cost-effectiveness analysis of initiating HIV/AIDS treatment with efavirenz-based regimens compared with nevirapine-based regimens in Thailand.
Artículo en Inglés | IMSEAR | ID: sea-38822
ABSTRACT

OBJECTIVES:

The aim of this study is to evaluate the cost-utility of the treatment, starting with EFZ-based therapy, compared with NVP-based therapy in Thai HIV/AIDS patients. MATERIAL AND

METHOD:

The study adopted a health care provider perspective. A probabilistic Markov model was applied to Thai HIV/AIDS patients aged 15 to 65 years. Input parameters were extracted from a cohort study of four regional hospitals. The study explored the effects of uncertainty around input parameters.

RESULTS:

For those patients with a different baseline CD4, initial therapy using EFZ-based regimens was the preferable choice for all subgroups. Given a maximum acceptable willingness to pay (WTP) threshold of 300,000 Baht/DALY averted starting with EFZ-based regimens was cost-effective for patients with a baseline CD4 count less than 250 cells/mm3 and in all patient age groups, except those who were 20 years old.

CONCLUSIONS:

The results suggest that starting with EFZ-based regimens was the preferable choice and it should be used as the first line regimen for Thai HIV/AIDS patients.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Tailandia / Anciano / Femenino / Humanos / Masculino / Infecciones por VIH / Probabilidad / Estudios de Cohortes / Cadenas de Markov / Adolescente Tipo de estudio: Estudio de etiología / Evaluación Económica en Salud / Estudio de incidencia / Estudio observacional / Estudio pronóstico / Factores de riesgo País/Región como asunto: Asia Idioma: Inglés Año: 2008 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Tailandia / Anciano / Femenino / Humanos / Masculino / Infecciones por VIH / Probabilidad / Estudios de Cohortes / Cadenas de Markov / Adolescente Tipo de estudio: Estudio de etiología / Evaluación Económica en Salud / Estudio de incidencia / Estudio observacional / Estudio pronóstico / Factores de riesgo País/Región como asunto: Asia Idioma: Inglés Año: 2008 Tipo del documento: Artículo