A cost-benefit of gnRH stimulation test in diagnosis of central precocious puberty (CPP).
Artículo
en Inglés
| IMSEAR
| ID: sea-38945
ABSTRACT
The GnRH stimulation test is the gold standard to diagnose central precocious puberty (CPP). Conventionally, we need at least 2 hours to finish the test which seems to be costly and time consuming. In this study, we described the pattern of LH and FSH levels during the GnRH test in 27 girls who presented with various degrees of precocious puberty. We found that the blood samples at 90 and 120 min after GnRH were not necessary. To save the cost of diagnosis, the basal LH/FSH ratio > 0.2, the 30 min LH/FSH ratio after GnRH > 0.9 and the peak LH/FSH ratio > 1.0 can be used to diagnose CPP with positive predictive values (PPV) of 87.3, 89.4 and 93.8 per cent respectively.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Pubertad Precoz
/
Femenino
/
Humanos
/
Hormona Luteinizante
/
Ensayo Inmunorradiométrico
/
Niño
/
Hormona Liberadora de Gonadotropina
/
Técnicas de Diagnóstico Endocrino
/
Fármacos para la Fertilidad Femenina
/
Hormona Folículo Estimulante
Tipo de estudio:
Evaluación Económica en Salud
/
Estudio pronóstico
Idioma:
Inglés
Año:
2000
Tipo del documento:
Artículo
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