Acute lupus hemophagocytic syndrome: report of a case and review of the literature.
Artículo
en Inglés
| IMSEAR
| ID: sea-39597
ABSTRACT
The authors reported a case of systemic lupus erythematosus (SLE) with an unusual presentation. The patient presented with acute febrile illness along with progressive pancytopenia related to increasing hemophagocytic activity of histiocytes in the bone marrow. Concomitant polyarthritis, myositis, nephritis, high titer of antinuclear factor (12,560) and positive test for anti-DNA antibody made him fit the diagnostic criteria of SLE. No definite evidence of associated infections was confirmed by bacteriologic, serologic and viral studies. He did not respond to empiric antibiotic therapy but dramatically responded to corticosteroid treatment. Therefore, diagnosis of acute lupus hemophagocytic syndrome was made. The clinical presentation, laboratory diagnosis, and management of the patient are discussed and the literature was reviewed and presented.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Pancitopenia
/
Fagocitosis
/
Médula Ósea
/
Humanos
/
Masculino
/
Prednisolona
/
Enfermedad Aguda
/
Adulto
/
Diagnóstico Diferencial
/
Lupus Eritematoso Sistémico
Tipo de estudio:
Estudio diagnóstico
Idioma:
Inglés
Año:
2004
Tipo del documento:
Artículo
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