Pathologically different features and fibrosis scores in chronic hepatitis C genotypes 3 and 1.
Artículo
en Inglés
| IMSEAR
| ID: sea-40548
ABSTRACT
BACKGROUND:
Chronic hepatitis C genotypes 3 and 1 are the two most common genotypes in Thailand.OBJECTIVE:
Identify the pathologically different features between genotypes 3 and land to compare the fibrosis score of Knodell HAI and Ishak modified HAI. MATERIAL ANDMETHOD:
The pathological features of 114 liver biopsies were evaluated.RESULTS:
Steatosis was more commonly found in genotype 3 than in genotype 1 (97.1% vs. 77.8%, p = 0.001). Portal lymphoid follicles were commonly found, but bile duct damage was uncommon. The majority of portal tracts showed partial involvement. The majority of patients had Knodell fibrosis 1 and Ishak fibrosis 3.CONCLUSION:
Steatosis is significantly more common in genotype 3, while other features do not show any differences. The portal tracts show partial involvement because inflammatory cells tend to aggregate and form lymphoid follicles. The most comparable fibrosis scores are Knodell fibrosis 1 and Ishak fibrosis 3.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Tailandia
/
Biopsia
/
Índice de Severidad de la Enfermedad
/
Femenino
/
Humanos
/
Masculino
/
Hepacivirus
/
Adulto
/
Hepatitis C Crónica
/
Hígado Graso
Tipo de estudio:
Estudio pronóstico
País/Región como asunto:
Asia
Idioma:
Inglés
Año:
2007
Tipo del documento:
Artículo
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