Immunonutrition and cytokine response in patients with head injury.
Artículo
en Inglés
| IMSEAR
| ID: sea-40569
ABSTRACT
BACKGROUND:
To investigate whether short-term postoperative immunonutrients feeding can modulate the level of cytokines in patients with head injury compared to standard enteral tube feeding formula. MATERIAL ANDMETHOD:
A randomized double-blind study was carried out on 40 moderate to severe head injury patients. They were randomized to have continuous nasogastric tube feeding within 24 hours after surgery of either the immunonutrient containing enteral formula (group A) or the standard enteral formula (group B). The level of interleukin-6 (IL-6) and 10 (IL-10) were measured on day 1 (before feeding), and subsequently on day 3 and day 5.RESULTS:
Twenty patients were randomly selected in each group, who had similar severity levels of injury. Compared to the level of IL-6 on day 1, the level of IL-6 was markedly reduced on day 3 in group A (p = 0.002), whereas such reduction in group B was not statistically significant.CONCLUSION:
Short term postoperative immunonutrient feeding can reduce cytokine level, indicating that systemic inflammatory response syndrome might be modulated by such feeding.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Anciano
/
Femenino
/
Humanos
/
Masculino
/
Alimentos Formulados
/
Método Doble Ciego
/
Adolescente
/
Interleucina-6
/
Interleucina-10
/
Nutrición Enteral
Tipo de estudio:
Ensayo Clínico Controlado
Idioma:
Inglés
Año:
2009
Tipo del documento:
Artículo
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