Loss of heterozygosity for chromosome 11 in Epstein-Barr-virus associated nasopharyngeal carcinoma.
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| ID: sea-40605
In order to demonstrate and define possible tumor suppressor gene loci on chromosome 11 associated with NPC, we used 7 STR to test for LOH on 25 NPC samples. LOH was detected in 46 per cent of cases. Most LOH loci were clustered on the long arm. Further study demonstrated 22 per cent and 45.5 per cent of cases with LOH on 11q13 and 11q23 respectively.
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Asunto principal:
Infecciones Tumorales por Virus
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Cromosomas Humanos Par 11
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Humanos
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ADN de Neoplasias
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ADN Viral
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Secuencias Repetitivas de Ácidos Nucleicos
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Neoplasias Nasofaríngeas
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Reacción en Cadena de la Polimerasa
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Cartilla de ADN
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Herpesvirus Humano 4
Idioma:
En
Año:
1996
Tipo del documento:
Article