Efficacy of benzimidazole carbamate on an intestinal fluke co-infected with nematodes.
Artículo
en Inglés
| IMSEAR
| ID: sea-42270
ABSTRACT
The efficacy of a single dose of benzimidazole, drugs commonly used for the treatment of Ascaris and hookworm, was evaluated against one of the tiny-sized intestinal flukes, Haplorchis sp in the endemic area where mixed infections of roundworms and flatworms existed. At day 7 after treatment, albendazole (400 mg) induced 42.5% cure rate, mebendazole (500 mg) a cure rate of 32.4%, on the other hand, praziquantel (40 mg/kg) gave 94.6% cure rate and the placebo at 15.9%. At the single dose, benzimidazole could not completely expelled the haplorchid; but could reduce one third to two fifth of the infection, similar to the drugs efficacy against Trichuris infection.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Praziquantel
/
Tailandia
/
Bencimidazoles
/
Humanos
/
Albendazol
/
Resultado del Tratamiento
/
Helmintiasis
/
Parasitosis Intestinales
/
Mebendazol
/
Antihelmínticos
Tipo de estudio:
Ensayo Clínico Controlado
País/Región como asunto:
Asia
Idioma:
Inglés
Año:
2005
Tipo del documento:
Artículo
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