Intravenous immunoglobulin prophylaxis for infection in very low birth-weight infants.
Artículo
en Inglés
| IMSEAR
| ID: sea-43599
ABSTRACT
The effectiveness of intravenous immunoglobulin for prevention of sepsis in very low birth weight infants was studied on 102 neonates at the Children Hospital, Bangkok from February 1988 to February 1990. Infants were randomly allocated into 3 groups of 35 each. Group I and group II received 250 mg/kg and 500 mg/kg of immunoglobulin intravenously respectively within four hours of life. Group III was not given immunoglobulin and served as the control group. It was found that during the early neonatal period the infection rate of group I (14.7%) and group II (14.7%) was significantly lower than that of group III (38.2%). There was no difference in the infection rate of group I and group II. The mortality rate was also higher in group III than in group I and group II. It suggested that the intravenous immunoglobulin dosage of 250 mg per kilogram body weight is effective as well as dosage of 500 mg per kilogram body weight in prevention of sepsis in very low birth weight infants during the early neonatal period.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Humanos
/
Inmunoglobulina G
/
Recién Nacido de Bajo Peso
/
Recién Nacido
/
Control de Infecciones
/
Inyecciones Intravenosas
Tipo de estudio:
Ensayo Clínico Controlado
Idioma:
Inglés
Año:
1991
Tipo del documento:
Artículo
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