Angiographic follow-up of genous bioengineered stent in acute myocardial infarction (GENAMI)-a pilot study.
Indian Heart J
;
2008 Nov-Dec; 60(6): 532-5
Artículo
en Inglés
| IMSEAR
| ID: sea-4797
ABSTRACT
OBJECTIVE:
GENAMI, an angiographic follow-up study was undertaken to evaluate the safety and efficacy of a new generation endothelial progenitor cell (EPC) capture stent, GENOUS during primary angioplasty for ST-elevation myocardial infarction (MI).METHODS:
Eleven consecutive patients with acute ST-elevation MI underwent primary percutaneous coronary intervention (PCI) using a bio-engineered GENOUS EPC stent.RESULTS:
Procedural success was 100%. Ten patients who survived underwent a follow-up angiography at 8 months. There was no instance of stent thrombosis during the follow-up period up to 12 months. The quantitative angiographic (quantitative coronary analysis [QCA]) follow-up data showed a late loss at 8 months of 0.97 +/- 0.94 mm and the late loss index was 44.35 +/- 40.47% with angiographic restenosis seen in 5 of 10 patients (50%). One of these patients with provocable ischemia underwent repeat PCI.CONCLUSIONS:
The QCA data of this study shows a high late loss with frequent angiographic restenosis during follow-up with this stent during primary PCI for acute STEMI. This observation, with important clinical implications, needs to be confirmed in larger studies.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Células Madre
/
Trombosis Coronaria
/
Anciano
/
Femenino
/
Humanos
/
Masculino
/
Angioplastia Coronaria con Balón
/
Stents
/
Proyectos Piloto
/
Estudios Prospectivos
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Idioma:
Inglés
Revista:
Indian heart j
Año:
2008
Tipo del documento:
Artículo
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