Methoxyphenyl maleamic acid augments the activity of cytotoxic drugs against murine tumours.
Indian J Cancer
;
1991 Mar; 28(1): 22-6
Artículo
en Inglés
| IMSEAR
| ID: sea-49320
ABSTRACT
The anti-tumour effects of methoxyphenyl maleamic acid (MPMA) and cytotoxic drugs, in combination were investigated on P388 leukaemia and S180 (ascites) tumours. Simultaneous administration of MPMA with CTX or HN2 resulted in enhancement of anti-tumour activity. The increased activity was observed against P388 leukaemia, whereas S180 (ascites) tumour was not responsive to the combined treatment. The possible mechanism (s) of action, responsible for the modulation of activity of CTX and HN2 against P388 tumour have been postulated.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ascitis
/
Leucemia P388
/
Protocolos de Quimioterapia Combinada Antineoplásica
/
Ciclofosfamida
/
Sinergismo Farmacológico
/
Animales
/
Maleatos
/
Mecloretamina
/
Ratones
Idioma:
Inglés
Revista:
Indian J Cancer
Año:
1991
Tipo del documento:
Artículo
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