Hairy cell leukaemia. A review of nine cases.
Indian J Cancer
;
1991 Sep; 28(3): 155-61
Artículo
en Inglés
| IMSEAR
| ID: sea-50416
ABSTRACT
Nine consecutive patients with HCL seen over a period of five years were reviewed. Male Female ratio was 81. Median age at diagnosis was 49 years. Weakness and fatigue (66%) were the commonest presenting symptoms and splenomegaly (66%) was the commonest physical findings. Varying degrees of pancytopenia was the consistent feature in majority of cases. Diagnosis was made on the basis of bone marrow biopsy and characteristic EM picture. Forty-four percent of cases developed serious infection during their clinical course. Gram negative bacilli and fungi were the most frequently isolated organisms. Major sites of infections were pneumonia and septicemia. Splenectomy was carried out in four cases. Rapid recovery of haematological parameters without any significant complication was observed in all these cases. Two patients were treated with alfa-interferon. In both the cases recovery of haematological parameters was slow compared to those under going splenectomy. One patient treated with alfa-interferon died due to infection related complications while the other went into remission.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Esplenectomía
/
Vincristina
/
Anciano
/
Femenino
/
Humanos
/
Masculino
/
Prednisona
/
Leucemia de Células Pilosas
/
Protocolos de Quimioterapia Combinada Antineoplásica
/
Preescolar
Idioma:
Inglés
Revista:
Indian J Cancer
Año:
1991
Tipo del documento:
Artículo
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